Combatting Antimicrobial Resistance in Africa Using Data Science

The CAMRA project is a comprehensive field-to-laboratory investigation of Nigerian and Rwandan children with serious bacterial infections (SBI). It aims to characterize the distribution and determinants of antimicrobial resistance (AMR) among Enterobacterales and the diseases they cause by prospectively enrolling hospitalized newborns, infants, and children with severe bacterial infection syndromes.

Project Objectives:

Analyze the phenotypic and genotypic profiles of Enterobacterales isolates from Nigeria and Rwanda.
Correlate multidrug-resistant organism (MDRO) status with the clinical course and outcomes of infected patients.
Determine household reservoirs of MDROs.